FREQUENCY OF PERIPROCEDURAL MYOCARDIAL INFARCTION IN PATIENTS UNDERGOING ELECTIVE PERCUTANEOUS CORONARY INTERVENTION
Keywords:Periprocedural Myocardial infarction, Percutaneous Coronary Intervention, Creatine kinase
AbstractObjective: To determine the frequency of periprocedural myocardial infarction in
patients undergoing elective percutaneous coronary intervention.
Methodology: In this study 100 patients with an indication for elective PCI
admitted in CCU at civil hospital Karachi were studied. Cardiac biomarker
measurements were scheduled before PCI and 6 hours after PCI, with
subsequent serial measurements for relevant biomarker increases or complaints
until peak increase was established. We used the PMI definition from the third
universal definition of MI: creatine kinase (CK-MB )3 times upper limit of normal.
All statistical analyses were performed with SPSS 12.0 Frequency was
calculated using chi-square.
Results: Patients in the study population had more diabetes mellitus (29% vs
16%, p< 0.001), hypertension (61% vs 51%, p <0.001), hypercholesterolemia
(66% vs 54%, p <0.001), and family history of coronary artery disease (57% vs
50%, p < 0.01) Of the study population (29%) had a history of diabetes mellitus.
PMI occurred in 5% of the study population. PMI occurred in five patients, 1 with 3
stents, 2 with 2 stents and 1 with 3 stents.
Conclusion: Frequency of PMI is low and is directly correlated with number of
stents implanted. This needs to be confirmed in larger studies.