THE EFFECT OF VIGOROUS PHYSICAL ACTIVITY ON INFLAMMATORY BIOMARKERS
Keywords:Key Words, Exercise, hs-CRP, Fibrinogen, D-dimer
AbstractObjective: To compare the effect of vigorous physical activity on inflammatory
biomarkers levels on football players and untrained people.
Mathodology: In this case control study, 44 men were enrolled .The case group
included 22 football players of Rafsanjan team that regularly exercised for 3 hours
per day. The control group(20 participants) were carefully selected healthy men
who were not engaged in any regular structured exercise activity and did not have
physically demanding jobs (e.g. manual labor). All participants underwent a
physician supervised maximal treadmill test. ESR, Fibrinogen, Ferritin, D-Dimer
and CRP were measured 15 minutes before exercise test.
Results: A total of 44 participants with mean age 22.00±0.6 were evaluated.
Serum levels of fibrinogen and D-dimer level were significantly lower in untrained
(p=0.003) and (p = 0.002) respectively. Moreover in football players group, hs-
CRP levels were significantly lower than the untrained (p = 0.000). However,
serum ferritin levels were lower in the athletes group than the untrained but the
difference was not significant (p = 0.3). ESR was slightly higher in the trained
group but the difference was not significant (p = 0.4).
Conclusion: Exercise decreased the levels of inflammatory biomarkers as hs-
CRP, but increased the levels of fibrinogen and D-dimer.