CORONARY ANGIOGRAPHIC CHARACTERISTICS OF CORONARY ARTERY DISEASE IN YOUNG ADULTS UNDER AGE FORTY YEARS COMPARE TO THOSE OVER AGE FORTY

Authors

  • Tahir Saghir
  • NADEEM QAMAR
  • JAVAID SIAL

Keywords:

Atherosclerosis, Coronary Disease, Risk Factor, Coronary Angiography, Young Adult.

Abstract

Objective: To compare the coronary angiographic characteristics of coronary artery disease in young
patients of less than and equal to 40 years of age with those of more than 40 years of age.
Patients and Methods: Observational study conducted from Sept to Jan 2003-2004.
A total of 299 patients of Coronary Artery Disease were included in the study. 102 patients were in less than
and equal to 40 years of age (group 1) and 197 patients were in greater than 40 years of age (group II).All
patients were selected according to inclusion and exclusion criteria. All demographic and clinical variables
and laboratory investigations were recorded for each patient. Coronary angiographic characteristics were
recorded and analyzed for each group.
Results: Study result showed that more patients in group I had single vessel disease than patients in group
II 39% vs 15% respectively, which was statistically significant P=0.001, while patients in group II had more
double, triple and LM disease as compared to group I 35% vs 20% (P=0.04), 25% vs 12% (P=0.03) and 9%
vs 2% (P=0.03) respectively. There was statistically no significant difference between the groups in terms of
baseline demographic and clinical variables except for angina class and DM. Group I had more angina class-
I patients 51% vs 25% than group II (P=0.003), while group II had more patients with DM 36% vs 14% than
in group I (P=0.002). There was no difference between the groups in terms of length of lesions and types of
lesions determined by coronary angiography and predilection for invovment. The most common effected
vessel was LAD followed by RCA and CX.
Conclusion: It is evident from present study that young patients of CAD have less extensive disease. CAD in
young person is more prevalent in those who smoke and had deranged lipid profile.

Downloads