IMPACT OF LEFT VENTRICULAR DYSFUNCTION ON THE OCCURRENCE OF VENTRICULAR ARRHYTHMIAS AFTER ACUTE ST ELEVATION MYOCARDIAL INFARCTION
Objective: The objective of the study was to compare the incidence of post STEMI ventricular arrhythmias among patients with versus without LV dysfunction.
Methodology: This prospective Cohort study was conducted in the department of cardiology of a tertiary care hospital, Isra University Hospital, Hyderabad over a period of eleven months from 1st September 2019 to 31st July 2020 and recruited a total of 95 patients with STEMI. Baseline data (age, gender, social class, and marital status) and clinical data (basal metabolic rate, systolic and diastolic blood pressure, random blood sugar, and LVSD) were recorded in a pre-structured questionnaire and analyzed using Statistical Package for the Social Sciences (SPSS) version 21 to see the comparative incidence of ventricular arrhythmias by applying chi-square test where applicable.
Results: Out of total 95 STEMI patients, 53 patients had left ventricular systolic dysfunction (55.7%). The overall incidence of ventricular arrhythmias was 23.1% and it was significantly higher in patients with LVSD as compared to those with normal LV function, 36.3% and 72.7% respectively (p = 0.001).
Conclusion: Our study shows that overall burden of ventricular tachyarrhythmias is two times higher in patients with left ventricular systolic dysfunction as compared to normal left ventricular systolic function.