ECHOCARDIOGRAPHIC FINDINGS IN HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY (HOCM)
Keywords:HOCM, MR, AR, LVOT gradient, LA diameter, Interventricular Septum
AbstractObjective: To find out various Echocardiographic findings in patients with HOCM.
Methodology: This was a retrospective cross-sectional study performed in
Cardiology department Lady Reading Hospital, Peshawar. Data collected from
the database computer section of echocardiography department from February
2009 to November 2011.The data was analyzed using SPSS version 14.
Results: Total study population was 28. Male were 14 (50%). Mean age was
52.5± 15.9 years. Mean left ventricular end diastolic dimension was 3.84cm;
inter-ventricular septal thickness 2cm (1.1-3.1) and posterior wall thickness was
1.17cm (0.6-1.6). Mean Left atrial (LA) diameter was 3.86cm (0.8-5.6). Mean
peak gradient across LVOT was 48.43 mmHg. Mitral regurgitation (MR) was
found in 19 (67.9%) patients. MR was mild in 57.1%, moderate in 7.1% and
severe in 3.6% of patients. Aortic regurgitation (AR) was found in 13 (46.4 %)
patients. AR was mild in 35.7%, moderate in 10.7% of patients. Left atrial size
was increased in 14 (50%) patients. Mean LA diameter was 4.6cm, 5cm and
5.6cm in patients with mild, moderate, and severe MR respectively. So there was
direct relation between severity of MR and LA diameter. The respective mean
gradient across LVOT in patients mild, moderate and severe MR was 31mmHg,
43.5mmHg and 140mmHg. So higher the gradient across LVOT, more will be the
MR and hence the LA size and the patient will be more symptomatic.
Conclusion: HOCM is significantly associated with both MR and AR and there is
direct relation between severity of MR with LA diameter and LVOT gradient.