RETINAL NERVE FIBER LAYER THICKNESS IN NON-GLAUCOMATOUS PAKISTANI CHILDREN
Keywords: Retinal nerve fiber layer, Glaucoma, Intraocular pressure, Normative values
AbstractObjective: To find out the normal retinal nerve fiber layer thickness in Pakistani children and create a normative data. Methodology: This descriptive cross sectional study was carried out at the Department of Pediatric Ophthalmology and Strabismus, Al-Shifa Trust Eye Hospital, Rawalpindi. The subjects were thoroughly examined by consultant pediatric ophthalmologist including slit-lamp examination, intraocular pressure (IOP) measurement, central corneal thickness (CCT) by handheld pachymeter and cycloplegic refraction. Those subjects who fulfilled the inclusion criteria were then sent for peripapillary retinal nerve fiber layer (RNFL) analysis by using spectral domain optical coherence tomography. RNFL thickness of 4 sectors were recorded and used for analysis which were temporal (T), nasal (N), superior (S) and inferior (I). Global (G), temporal superior (TS), temporal inferior (TI), nasal superior (NS) and nasal inferior (NI) were also included. Results: A total of 106 eyes of 53 subjects were included in the study. Male were 28 (52.8%); mean age, IOP and CCT were 10.78± 2.61 years, 13.11 ±2.3 mm Hg and 542.31 ±43.9 microns respectively. Mean RNFL-Global was 101.25 microns with male having more thickness as compared to females (103.7 ±10.15 versus 99.87 ±8.47), p =0.17. Conclusion: Mean RNFL-Global was 101.25 microns with male having more thickness as compared to females but not significant. These results can be used as reference when evaluating the normal values of RNFL in our pediatric population.